Senior Director, Translational Research & Clinical Development

Job description

About the Client:

Our client is a prominent, diversified global biotechnology company with a strong commitment to improving health and wellness through innovative science. With a substantial portfolio spanning human health, and agricultural biotechnology, they are dedicated to discovering, developing, and commercializing therapies that address significant unmet medical needs.

They're seeking an exceptional and visionary Senior Director, Translational Research & Clinical Development to lead and integrate our client's early-stage development pipeline. This is a key leadership role responsible for bridging the gap between preclinical discovery and clinical proof-of-concept.

Job Responsibilities:

You will be responsible for the design and execution of translational strategies, oversight of IND-enabling studies, and the clinical development of assets through Proof-of-Concept (Phase II). You will ensure that every program is built on a foundation of robust science, clear biomarker strategies, and regulatory alignment.

• Lead the creation of integrated development plans for novel assets, ensuring a seamless transition from preclinical candidates to First-in-Human (FIH) trials.
• Champion the interrogation of preclinical data to identify critical translational questions, define target product profiles, and select optimal clinical indications.
• Drive the identification and validation of pharmacodynamic, predictive, and prognostic biomarkers to support clinical differentiation and regulatory approval.
• Provide strategic scientific leadership for the design, initiation, and management of Phase I and Phase II clinical studies.
• Oversee the conduct of GLP toxicology studies and other regulatory-enabling work packages.
• Act as the key scientific liaison between the clinical operations team and research function, ensuring that study protocols answer fundamental scientific hypotheses while remaining operationally feasible.
• Lead the authoring, review, and submission of key regulatory documents, including INDs/CTAs, Investigator's Brochures, and Clinical Study Reports.
• Participate in health authority meetings and respond to regulatory inquiries regarding translational and early clinical data packages.
• Ensure all clinical and translational activities adhere to GCP, GLP, and global regulatory standards.
• Build and manage relationships with Key Opinion Leaders (KOLs), academic collaborators, and Clinical Research Organizations (CROs) to enhance program credibility and execution.
• Represent the company's pipeline at major scientific congresses, investor meetings, and with potential licensing partners.
• Lead the development of high-impact publications and presentations to communicate the scientific value of the portfolio.

Candidate Profile:

• MD, PhD, or MD/PhD in a relevant life sciences discipline.
• Minimum of 8-10 years in the biopharmaceutical or biotechnology industry with a dedicated focus on translational medicine and early clinical development.
• Proven history of successfully advancing at least one asset from the research phase into clinical development (IND/CTA approval). Experience managing programs through Phase II is highly desirable.
• Deep expertise in translational science, including biomarker development, clinical pharmacology, and experimental medicine. Ability to critically evaluate complex datasets and make rapid, data-driven decisions.
• A visionary thinker capable of designing competitive clinical development plans that account for regulatory pathways, commercial landscapes, and patient needs.
• A natural collaborator who can work effectively in a matrix environment, influencing peers and senior leaders without direct authority. Experience managing and mentoring small, high-performing teams.

What to Expect:

Our client offers the benefits of a work environment that is stimulating, challenging and balanced. It makes sure that you will be working in highly visible and being part of an Employee & Engineer work that provides a large degree of autonomy to their management team and encourages creativity and development of new ideas.

Insert & Apply:

This a golden opportunity within a Multinational Company (MNC) excellent career prospect. If you are interested, please send your resume